Read a description of this diagram
The diagram sets out four linked boxes. Box A, risk factors, lists examples such as functional impairments, stigma, life transitions, role loss, economics and societal barriers.
Box B, social connections, is broken down into three dimensions: structure, for example network size and living status; function, for example social support and social roles; and quality, for example relationship satisfaction and strain.
Box C, mechanisms, holds the three pathways described above. Psychological covers stress, resilience and meaning. Biological covers inflammation and immune function. Behavioural covers physical activity, sleep, nutrition and medical adherence, and also risk-taking, violence and self-harm.
Box D, outcomes, is split between illness — physical such as cardiovascular disease and diabetes, mental such as depression and anxiety, and cognitive such as dementia — and mortality, covering all-cause, natural deaths from disease, and unnatural deaths from accidents, homicide and suicide.
Risk factors feed into social connections, which act on the mechanisms, which in turn act on illness and mortality. A separate line runs from social connections directly to outcomes, bypassing the mechanisms, and a dotted line across the top connects risk factors and outcomes. The arrows between the mechanisms and the outcomes point both ways, so the relationships are cyclical rather than one-directional.